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Pronounced: i-MA-tin-ib Classification: Tyrosine Kinase Inhibitor. About Imatinib. Imatinib works by blocking signals within cancer cells, which prevents a series of …
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imatinib mesylate The mesylate salt of imatinib, a tyrosine kinase inhibitor with antineoplastic activity. Imatinib binds to an intracellular pocket …
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Inhibition of Polysome Assembly Enhances Imatinib Activity against Chronic Myelogenous Leukemia and Overcomes Imatinib Resistance
Expert Opin Investig Drugs (2009) 18: 457-68. Treatment of gastrointestinal stromal tumours: imatinib, sunitinib — and then?
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Imatinib can be taken by mouth in dosages of 100 mg or 400 mg. The 100 mg is usually orange in color and round shape; the 400 mg comes in an orange scored oblong.
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Guidance TA241 Dasatinib, high-dose imatinib and nilotinib for the treatment of imatinib-resistant chronic myeloid leukaemia (CML) (part review of NICE technology …
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Imatinib works because p210bcr-abl requires a molecule of ATP to activate tyrosine residues on its substrates by phosphorylation. Imatinib instead docks in to this …
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Imatinib – Imatinib interferes with the growth of some cancer cells. – Do not use imatinib if you are pregnant. It could harm the unborn baby.
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